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Idexx Acth Stim. SNAP Combo Plus Test IDEXX Veterinary Diagnostics IDEXX Norway Advantages-The ACTH stimulation test is the best screening test for distinguishing spontaneous from iatrogenic hyperadrenocorticism Equivocal, Normal Cushing's possible If both results are <2 µg/dL, results are consistent with hypoadrenocorticism Inconclusive Pre- and Post-ACTH <2 µg/dL Post-ACTH >22 µg/dL Post-ACTH 2-6 µg/dL Pre-ACTH: 2-6 µg/dL

IDEXX SNAPshot DSR Reader TECHNOPATH
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The testing procedure is detailed in the ACTH Stimulation Technique box, with results interpreted as follows: Refer to laboratory's diagnostic cutoffs for interpretation ACTH stimulation (pre and post) Canine Normal pre-ACTH (resting) cortisol: 0.5-4.0 µg/dL Normal post-ACTH cortisol: 8.0-20 µg/dL Equivocal for hyperadrenocorticism post-ACTH cortisol: 18-22 µg/dL Post-ACTH cortisol consistent with hyperadrenocorticism: > 22 µg/dL

IDEXX SNAPshot DSR Reader TECHNOPATH

If the 1 hr post-ACTH cortisol exceeds 22 mcg/dL, this is consistent with CS. Recheck at one month History, physical exam, chemistry panel, and electrolytes If the 1 hr post-ACTH cortisol exceeds 22 mcg/dL, this is consistent with CS.

Treatment of PituitaryDependent Hyperadrenocorticism. Therefore, in order to obtain results at the peak time of effect, the ACTH stimulation test should be performed at 4-6 hours post-dosing In spontaneous hyperadrenocorticism, the ACTH stimulation test reliably identifies more than 50 per cent of dogs with adrenal-dependent hyperadrenocorticism and about 85 per cent of dogs with pituitary-dependent.

Endocrine Evaluation Veterian Key. Perform ACTH stimulation test 4-6 hours after morning capsule Recheck at one month History, physical exam, chemistry panel, and electrolytes